Obstetric Vasculopathies

Obstetric vasculopathy refers to disease or disorders in the vessels occurring at the fetomaternal interface, resulting in obstetrical conditions such as preeclampsia, recurrent miscarriages, intrauterine growth retardation, recurrent stillbirths and accidental haemorrhage.

This book examines the complex and relatively unexplored area of obstetric vasculopathies. Beginning with an introduction to the subject and discussion on normal cardiovascular conditions in pregnancy, the following chapters describe the effects of obstetric vasculopathies on different organs, emphasising genetic and immunological aspects of the disease.

Clinical profile, prevention, differential diagnosis, prediction, technological assistance, such as colour Doppler and cardiotocography, and management of obstetric vasculopathies are discussed in depth.   

Key points

• Examines complex, relatively unexplored area of obstetric vasculopathies
• Describes normal cardiovascular conditions in pregnancy
• Details effect of obstetric vasculopathies on different organs, with emphasis on genetic and immunological aspects
• Clinical profile, differential diagnosis, technological assistance and management discussed in depth

1. General aspects of obstetric vasculopathies
2. Cardiovascular changes in normal pregnancy
3. Immunology of obstetric vasculopathy
4. Endothelial cell dysfunction and obstetric vasculopathy
5. Oxidative stress and obstetric vasculopathies
6. The placenta, the trophoblasts and obstetric vasculopathies
7. The genetics of obstetrics vasculopathies
8. Obstetric vasclopathies and their effects heart
9. Obstetric vasculopathies and their effects on the renal system
10. Obstetric vasculopathies and their effects on the central nervous system
11. Obstetric vasculopathies and their effects on hematological system
12. Obstetric vasculopathies and their effects on the liver
13. Ophthalmic features in obstetric vasculopathy
14. Vascular responses in obstetric vasculopathy
15. Clinical profile of obstetric vasculopathies
16. Differential diagnosis of obstetric vasculopathies
17. Predicting obstetric vasculopathies
18. Prevention of preeclampsia and other obstetric vasculopathies
19. Colour Doppler in obstetric vasculopathies
20. Cardiotocography (ctg) in obstetric vasculopathies
21. Treatment of obstetric vasculopathy: recurrent miscarriages
22. Treatment of obstetric vasculopathy: preeclampsia
23. Treatment of obstetric vasculopathy: accidental hemorrhage

Pankaj Desai MD FICOG FICMCH
Consultant and Specialist in Obstetrics and Gynaecology, Janani Maternity Hospital, Baroda, Gujarat, India